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Genetic Disease DNA Test

Genetic Disease DNA Test

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Description

For Veterinarians and Professionals only

Genetic Disease DNA Test identifies the mutation associated with a specific genetic disease. This test utilizes an automated and highly accurate molecular genetic method to determine the DNA sequence. Depending on the mode of inheritance, DNA test results will show that the animal is in one of three categories:

DNA mutation is Autosomal Recessive
Normal: DNA mutation associated with the specific genetic disease is not present. The animal will not develop the condition due to the specific DNA mutation and will not pass the mutation onto its offspring.
Carrier: The animal carries one copy of defective gene and one copy of normal gene. The animal will not develop the condition due to the specific DNA mutation but will pass the mutation onto its offspring 50% of the time.
Affected: The animal carries two copies of the defective gene. The animal is very likely to develop the condition due to the specific DNA mutations in its lifetime and will pass the mutation onto its offspring 100% of the time.

DNA mutation is Autosomal Dominant
Normal: DNA mutation associated with the specific genetic disease is not present. The animal will not develop the condition due to the specific DNA mutation and will not pass the mutation onto its offspring.
Carrier: The animal carries one copy of defective gene and one copy of normal gene. The animal is very likely to develop the condition due to the specific DNA mutation in its lifetime and will pass the mutation onto its offspring 50% of the time.
Affected: The animal carries two copies of the defective gene. The animal is very likely to develop the condition due to the specific DNA mutations in its lifetime and will pass the mutation onto its offspring 100% of the time.

Genetic Disease DNA tests are available for the following genetic disorders (please inquire if test is not listed below):

Canine
• Arrythmogenic Right Ventricular Cardiomyopathy (ARVC) 致心律失常性右室心肌病
• Cobalamin Malabsorption (B12) 鈷胺素吸收不良
• Cone Degeneration (CD) 視錐變性
• Collie Eye Anomaly (CEA) 柯利犬眼部異常
• Congenital Hypothyroidism (CH) 先天性甲狀腺機能減退
• Canine Leucocyte Adhesion Deficiency (CLAD) 犬白細胞黏附缺陷
• Congenital Myotonia (CM) 先天性肌强直
• Canine Multifocal Retinopathy Type 1 (CMR1) 犬多焦視網膜病變的類型1
• Cyclic Neutropenia / Gray Collie Syndrome (CN) 週期性嗜中性球減少症/ 灰色柯利犬綜合症
• Congenital Stationary Night Blindness (CSNB) 先天性靜止性夜盲症
• Copper Toxicosis (CT) 銅中毒
• Degenerative Myelopathy (DM) 退行性脊髓病
• Exercise Induced Collapse (EIC) 運動誘發性虛脫
• Fucosidosis (FCS) 岩藻糖苷儲積病
• Factor IX / Haemophilia B (FIX) 凝血因子IX缺乏/ 血友病B
• Familial Nephropathy (FN) 家族性腎病
• Factor VII Deficiency (FVII) 凝血因子 VII 缺乏
• Globoid Cell Leukodystrophy (GCL)/ Krabbe’s Disease 球形細胞腦白質營養不良/ 克拉伯•病
• Gangliosidosis (GM) 神經節苷脂儲積病
• Hereditary Cataracts (HC) 遺傳性白內障
• Hereditary Nephropathy (HN) 遺傳性腎病
• Hyperuricosuria (HUU) 高尿酸尿症
• Juvenile Dilated Cardiomyopathy (JDCM) 幼犬擴張性心肌病
• L-2-Hydroxyglutaric Acidiuria (L2-HGA) L-2-羥基戊二酸尿症
• Ivermectin and Multi Drug Sensitivity (MDR1) 伊維菌素及多藥敏性
• Malignant Hyperthermia (MH) 惡性高熱
• Musladin-Lueke Syndrome (MLS)
• Mucopolysaccharidosis (MPS) 粘多醣貯積病
• Mucopolysaccharidosis VII (MPS VII) 粘多醣貯積病 VII型
• Multifocal Retinopathy (MR) 多焦視網膜病變
• Narcolepsy (NARC) 嗜睡症
• Neonatal Cortical Cerebellar Abiotrophy (NCCD) 新生犬小腦營養不良
• Neuronal Ceroid Lipofuscinosis (NCL) 神經元蠟樣脂褐質貯積病
• Neonatal Encephalopathy with Seizures (NEWS) 新生犬腦病
• Osteogenesis Imperfecta (OI) 成骨不全症
• Pyruvate Dehydrogenase Phosphatase 1 Deficiency (PDP1) 丙酮酸脫氫磷酸酶缺一乏症
• Phosphofructokinase Deficiency (PFK) 磷酸果糖激酶缺乏症
• Primary Hyperoxaluria (PHO) 原發性高草酸鹽
• Pyruvate Kinase Deficiency (PKDef) 丙酮酸激酶缺乏症
• Primary Lens Luxation (PLL) 原發性晶狀體脫位
• Primary Open Angle Glaucoma (POAG) 原發性開角型青光眼
• Severe Combined Immune Deficiency (SCID) 嚴重複合型免疫缺乏症
• von Willebrand's Disease ​​(vWD) 馮威利布蘭德病
Plus many more...

Feline
• Blood Group (BGB) B血型 
• Familial Episodic Hypokalaemic Polymyopathy (FEHP) 陣發性低血鉀多重肌肉病變
• Familial Hypertrophic Cardiomyopathy (HCM-MC) 肥厚性心肌病
• Familial Hypertrophic Cardiomyopathy (HCM-Rd) 肥厚性心肌病
• Gangliosidosis 1 (GM1) 神經節苷脂GM1貯積病
• Gangliosidosis 2 (GM2) 神經節苷脂GM2貯積病
• Polycystic Kidney Disease (PKD) 多囊性腎病
• Pyruvate Kinase Deficiency (PKDef) 丙酮酸激酶缺乏症
• Progressive Retinal Atrophy (PRA-rdAc) 漸進性視網膜萎縮
• Progressive Retinal Atrophy (PRA-Rdy) 漸進性視網膜萎縮
• Spinal Muscular Atrophy (SMA) 貓脊柱萎縮
Plus many more...

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